Inferring gene-to-phenotype and gene-to-disease relationships at Mouse Genome Informatics: challenges and solutions
2016
Background
Inferring gene-to-phenotype and gene-to-human disease model relationships from annotated mouse phenotypes and disease associations is critical when researching gene function and identifying candidate disease genes. Filtering the various kinds of genotypes to determine which phenotypes are caused by a mutation in a particular gene can be a laborious and time-consuming process.
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