Low folate status as a risk factor for cervical dysplasia in Thai women

Abstract The relationship between folate status and the risk of cervical dysplasia was studied among Thai women. The subjects were composed of 44 women with low-grade cervical neoplasia (cervical intraepithelial neoplasm I), 70 women with high-grade cervical neoplasia (cervical intraepithelial neoplasm II, III, and carcinoma in situ), and 95 women who served as controls. The low folate status in these women showed a strong association with cervical dysplasia. Serum folate was markedly lower in both low-grade ( P P