Pharmacotherapy of Thoracic Aortic Aneurysm

Aortic aneurysm is defined as a permanent focal aorta dilatation. with at least a 50 % increase in diameter compared with the expected normal diameter. Thoracic aortic aneurysms (TAA) may involve one or more aortic segments (aortic root, ascending aorta, arch or descending aorta). Sixty percent of TAAs involve the aortic root and/or ascending tubular aorta, 40 % the descending aorta, 10 % the arch, and 10 % the thoracoabdominal aorta. In the ascending aorta, genetic factors are of major importance and in the descending aorta, are the risk factors for atherosclerosis.