Specific antiproliferative activity against human cancer cells with metabolites from several species related to the genus Cordyceps

In current cancer therapies, anticancer drugs have the disadvantage of targeting a substantial number of normal as well as cancer cells. This nonspecific cellular toxicity causes severe side effects in patients with cancer. Majority of anticancer drugs used in the clinic were developed using metabolites derived from group A -hemolytic streptococcus (group A streptococcus) (Shen et al., 1992) or actinomycetes such as Streptomyces caespitosu (Taechowisan et al., 2007, ISSN: 2319-7706 Volume 3 Number 5 (2014) pp. 607-617 http://www.ijcmas.com