MiR-301a Mediates the Effect of IL-6 on the AKT/GSK Pathway and Hepatic Glycogenesis by Regulating PTEN Expression

Lin Dou,Shuyue Wang,Xiaofang Sui,Xiangyu Meng,Tao Shen,Xiuqing Huang,Jun Guo,Weiwei Fang,Yong Man,Jianzhong Xi,Jian Li

MiR-301a Mediates the Effect of IL-6 on the AKT/GSK Pathway and Hepatic Glycogenesis by Regulating PTEN Expression

2015

Lin Dou
Shuyue Wang
Xiaofang Sui
Xiangyu Meng
Tao Shen
Xiuqing Huang
Jun Guo
Weiwei Fang
Yong Man
Jianzhong Xi
Jian Li

Background/Aims: IL-6 has been implicated in the pathogenesis of insulin resistance. MiR-301a plays an important role in various biological and pathological proce

Keywords:

Protein kinase B
Glycogenesis
PI3K/AKT/mTOR pathway
Pathogenesis
PTEN
Cancer research
Signal transduction
Downregulation and upregulation
GSK-3
Biology
Phosphorylation

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