Problems with implementing a standardised transcranial Doppler screening programme: impact of instrumentation variation on STOP classification
2012
Background
The Stroke Prevention Trial in Sickle Cell Anaemia (STOP) demonstrated the value of selective transfusion based on transcranial Doppler (TCD) US screening. This facilitated widespread surveillance, but due to reported differences with non-imaging TCD, imaging velocity thresholds have been reduced in some centres.
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