[Influence of anxiogenic stress upon severity of alloxan-induced pancreatic and hepatic damage].

: 4 episodes of immobilization stress caused anxious and depressive behavioral disorder in rats, accompanied by decreased sensitivity of pancreatic tissue to alloxan-induced damage, and simultaneously increased sensitivity of hepatic tissue to alloxanogenic inflammatory effect. The latter shifts were accompanied by a more pronounced hyperglycemia. The paper discusses a probable role of hepatitis in hyperglycemic response to alloxan challenge associated with stressogenic anxiety.