A new correction for controlling family-wise error rate in multiple comparison studies

Misleading conclusions can be drawn from multiple comparison studies if the critical p value is set as equivalent to the preselected statistical α level. This incorrect assumption is observed in many research publications where not enough attention was paid to the inflation of the critical p value as a result of increasing the number of comparisons. A new approach is proposed to control the false discovery rate for independent comparisons. The new approach renders more reliable critical p values and allows reducing the inflated values to the original preselected α level.