5‐endo‐trig Cyclization of 1,1‐Difluoro‐1‐alkenes: Synthesis of 3‐Butyl‐2‐fluoro‐1‐tosylindole

o-(1,1-Difluorhex-1-en-2-yl)aniline o′-(1,1-Difluorohex-1-en-2-yl)-p-toluenesulfonanilide 3-Butyl-2-fluoro-1-tosylindole 2,2,2-Trifluoroethyl p-toluenesulfonate Trimethylamine oxide Tetrabutylammonium fluoride o-Iodoaniline Triphenylphosphine Tris(dibenzylideneacetone)dipalladium(0)-chloroform (1/1) Keywords: 5-endo-trig-cyclization; 1,1,-difluoro-1-alkenes; butyl-fluoro-tosylindole; intramolecular substitution; five-membered rings; Baldwin's rules; 2,2-difluorovinylboranes; difluorostyrenes; waste disposal