Enantioselective Intermolecular Heck Reaction of Aryl Triflates, Mesylates and Tosylates Catalyzed by Nickel

Nickel-catalyzed intermolecular Heck reaction of cycloalkenes proceeds well with aryl triflates, mesylates and tosylates in excellent enantiomeric ratios. The asymmetric reductive Heck reaction also works with a 2-cyclopentenone ketal,  which is equivalent to conjugate arylation of the enone itself.