Polysaccharide-based nanoparticles: a versatile platform for drug delivery and biomedical imaging.
2012
Polysaccharide-based nanoparticles have attracted interest as carriers for imaging and therapeutic agents because of their
unique physicochemical properties, including biocompatibility and biodegradability. In addition, the functional groups of the
polysaccharide backbone allow facile chemical modification to develop nanoparticles with diverse structures. Some polysaccharides have
the intrinsic ability to recognize specific cell types, facilitating the design of targeted-drug delivery systems through receptor-mediated
endocytosis. The main objective of this review is to provide an overview of various polysaccharide-based nanoparticles and to highlight
the recent efforts that have been made to improve the characteristics of polysaccharide-based nanoparticles for drug delivery and
biomedical imaging.
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