KOH‐Oriented Ring Openings of N‐Tosylaziridines with Carboxylic Acids in DMSO.
2015
A facile and efficient KOH-oriented regioselective ring-opening reaction for the acetolysis of N-tosylaziridines in DMSO was developed under mild conditions. This operationally simple protocol could tolerate a variety of functionalized carboxylic acids as well as several N-tosylaziridines. Moreover, this strategy provided the corresponding ring-opening products with good results.
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