Clinical Research Percutaneous vs Surgical Repair of Mitral Valve Regurgitation: Single Institution Early and Midterm Outcomes

Background: The objective of this study was to compare outcomes of surgical repair (SR) vs MitraClip (MC) implantation for severe mitral regurgitation (MR). Methods: A retrospective analysis of patients treated within a single institution was performed. Patients had EuroSCORE [European System for Cardiac Operative Risk Evaluation] 20%, left ventricular ejection fraction 45%, and grade 3/4 MR. Results: Fifty patients (24 [48%] MC group, 26 [52%] SR group) with EuroSCORE 7.9 5.6 were included. The MC group included 24 (48%) and the SR group 26 (52%) patients. Patients in the MC group had a significantly more complex comorbid profile (P 0.001). Successful MC placement was in 22 patients (91.7%) and SR in 26 (100%). At discharge, no patient had grade 3/4 MR. There were no in hospital or 30-day deaths. At follow-up (mean 526 398 days), further mitral valve surgery was necessary in 1 (3.8%) patient in the SR group and in 2 (8.3%) patients in the MC group (P 0.26). One-year freedom from composite end point (death, stroke, myocardial infarction, major