Improved ZAP-70 assay using two clones, multiple methods of analysis and clinical correlation.

Heba Degheidy,David Venzon,Mohammed Farooqui,Fatima Abbasi,Diane C. Arthur,Wyndham H. Wilson,Adrian Wiestner,M. A. Stetler-Stevenson,Gerald E. Marti

Improved ZAP-70 assay using two clones, multiple methods of analysis and clinical correlation.

2011

Heba Degheidy
David Venzon
Mohammed Farooqui
Fatima Abbasi
Diane C. Arthur
Wyndham H. Wilson
Adrian Wiestner
M. A. Stetler-Stevenson
Gerald E. Marti

Introduction In a companion methodological study, we compared two anti-ZAP-70 clones (1E7.2 AF 488 and SBZAP PE) and four selected methods of analysis. Clinical correlations are required for validation.

Keywords:

Immunology
Gene expression
Immunoassay
Chronic lymphocytic leukemia
ZAP-70 Protein-Tyrosine Kinase
Biology
Immunoglobulin heavy chain
Mutation
Molecular biology
Flow cytometry
Correlation
multiple methods
clinical correlation
antibodies monoclonal
methodological study

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