In vitro Enhancement by CpG ODN of Phagocytic Activity of Rainbow Trout Head Kidney Phagocytes against Fish Pathogen Vibrio ordalii, but not against Polystyrene Particles

Rainbow trout (Oncorhynchus mykiss) head kidney phagocytes precultured with a synthetic cytidine-phosphate-guanosine (CpG) oligodeoxynucleotide (ODN) displayed significantly higher phagocytic activity agaist Vibrio ordalii than phagocytes precultured with non-CpG ODN. However, head kidney phagocytes precultured with CpG ODN did not show enhanced phagocytic activity against polystyrene particles.