[Usefulness of low-dose irinotecan for multiple lung metastases of cholangiocellular carcinoma after operation--a case report].

2002 
: We treated a patient in whom low-dose irinotecan therapy was effective for the treatment of multiple lung metastases of cholangiocellular carcinoma after operation. The patient was a 50-year-old man. He underwent extended right hepatectomy for cholangiocellular carcinoma, and multiple lung metastases occurred 8 months after operation. For the treatment of lung metastases, low-dose irinotecan therapy (70 or 40 mg/week) was carried out. Eighteen months after the lung recurrence, he is still alive with a good quality of life, although the lung metastases have progressed. These results suggest that low-dose irinotecan therapy can be effective for lung metastases of cholangiocellular carcinoma.
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