Physalin F Induces Cell Apoptosis in Human Renal Carcinoma Cells by Targeting NF-kappaB and Generating Reactive Oxygen Species

Szu Ying Wu,Yann-Lii Leu,Ya-Ling Chang,Tian Shung Wu,Ping Chung Kuo,Yu Ren Liao,Che-Ming Teng,Shiow Lin Pan

Physalin F Induces Cell Apoptosis in Human Renal Carcinoma Cells by Targeting NF-kappaB and Generating Reactive Oxygen Species

2012

Szu Ying Wu
Yann-Lii Leu
Ya-Ling Chang
Tian Shung Wu
Ping Chung Kuo
Yu Ren Liao
Che-Ming Teng
Shiow Lin Pan

Background The aim of this study was to determine the molecular mechanisms of physalin F, an effective purified extract of Physalis angulata L. (Solanacae), in renal carcinoma A498 cells.

Keywords:

Carcinoma
Cancer research
Cell cycle
Immunology
Apoptosis
Phytotherapy
Physalis angulata
Reactive oxygen species
Mitochondrion
NFKB1
Biology
Cytochrome c
Molecular biology
Cytosol
MTT assay
Physalin

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