Oral conidiobolomycosis in a dog

Conidiobolomycosis was diagnosed via culture from an oral lesion in a 1.5-year-old German Shepherd dog. Clinically, the lesion consisted of a large, irregularly shaped, ulcerative focus on the caudal hard palate. Microscopically, the lesion was characterized by an eosinophilic granulomatous stomatitis with hyphal organisms surrounded by eosinophilic sleeves (Splendore–Hoeppli material) suggestive of an entomophthoramycosis. The fungus was cultured and identified with features consistent with Conidiobolus sp. Treatment with itraconazole at 10 mg kg−1 twice daily for 61 days resulted in clinical and radiographic resolution of the lesion.