Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation

2011

The argine methyltransferase PRMT5 methylates EGFR. This modification increases EGFR trans-autophosphorylation and attenuates ERK pathway activation.

Keywords:

Correction
Source
Cite
Save
Machine Reading By IdeaReader

126

References

165

Citations