Profound leukemia cutis in a patient with relapsed T-cell acute lymphoblastic leukemia

Leukemia cutis is defined as the cutaneous infiltration of neoplastic leukocytes in patients with underlying hematologic malignancies and has a heterogeneous clinical presentation.1 Most commonly, leukemia cutis presents with single or multiple erythematous papulonodules. Herein, we describe a unique clinical presentation of leukemia cutis in a patient with relapsed T-cell acute lymphoblastic leukemia (T-ALL). As the diagnosis of leukemia cutis has important treatment and prognostic implications, prompt clinical recognition and histopathologic confirmation is imperative.