Radial artery intima-media thickness regresses after secondary prevention interventions in patients’ post-acute coronary syndrome and is associated with cardiac and kidney biomarkers

// Damilola D. Adingupu 1 , Helena U. Westergren 1, 2 , Santosh Dahgam 1 , Ann-Cathrine Jonsson-Rylander 1 , Juuso Blomster 1, 2 , Per Albertsson 4 , Elmir Omerovic 4 , Sara Svedlund 2, 3 and Li-Ming Gan 1, 2, 4 1 AstraZeneca RD rIMT left 0.37 ± 0.08) vs. (rIMT right 0.29 ± 0.08; rIMT left 0.31 ± 0.09) respectively. There was no statistically significant change in cIMT. In healthy controls there were no changes in rIMT or cIMT overtime. High levels of CX3CL1 and myeloperoxidase measured within one month post ACS are associated with increase of rIMT, r=0.38 (p< 0.0001) and r=0.41 (p< 0.0001) respectively. Conclusions: rIMT seem to decrease systemically after ACS and is accompanied with corresponding biomarker change. The cause and clinical implications of the observed decrement in rIMT after ACS need further studies.