2-deoxy glucose: A ray of hope for treatment of covid-19
2021
2-Deoxy-D-glucose, mimic of glucose having deoxygenated carbon at second position i.e. hydroxyl group is replaced by hydrogen, due to which 2-DG cannot undergo further glycolysis. It inhibits the production of glucose-6-phosphate from glucose at the phosphoglucoisomerase level which is second step of glycolysis.
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