Bacteriochlorin Dyads as Solvent Polarity Dependent Near-Infrared Fluorophores and Reactive Oxygen Species Photosensitizers

Symmetrical, near-infrared absorbing bacteriochlorin dyads exhibit gradual reduction of their fluorescence (intensity and lifetime) and reactive oxygen species photosensitization efficiency (ROS) with increasing solvent dielectric constant e. For the directly linked dyad, significant reduction is observed even in solvents of moderate e, while for the dyad containing a 1,4-phenylene linker, reduction is more parallel to an increase in solvent e. Bacteriochlorin dyads are promising candidates for development of environmentally responsive fluorophores and ROS sensitizers.