Usefulness of severity predictive scores in COPD exacerbations in hospitalized patients

Introduction: There are new prognostic classifications in COPD exacerbation, BAP-65 and DeCOPD. Our objective was to evaluate the usefulness of this severity predictive scores in COPD exacerbations in hospitalized patients and determinate their relation with other factors. Methods: One year observational retrospective study in hospitalized patients with COPD exacerbation. The patients were classified according to the severity predictive scores BAP-65 and DeCOPD. We measured average stay in hospital, readmission at first and third month, FEV1, Karnofsky Index, C reactive protein and peripheral eosinophilia. Results: 183 patients were included in our study, all of them with de diagnostic of COPD exacerbation. In BAP-65 score (I: 14,8%, II: 46,4%, III: 33,3%, IV: 5,5% and V:0%), the mean stay (days) was higher in groups with worse prognosis (IV: 7,1), readmissions at first and third month higher in IV (55,5% and 77,7%), FEV1 lower in I (44,4%), Karnofsky Index lower in IV (73), C reactive protein higher in IV (14,9mg/dl) and peripheral eosinophilia higher in I (1,6%). In DeCOPD score (mild: 30,6%, moderate: 54,7%, severe: 14,2% and very severe: 0,5%) the mean stay was higher in groups with worse prognosis (7,48 days), readmission at first and third month higher in severe group (53,8% and 57,6%), FEV1 lower in moderate group (44,1%), Karnofsky Index lower in severe group (74,4), C reactive protein higher in severe group (12,4mg/dl) and peripheral eosinophilia higher in moderate group (1,1%). Conclusion: In hospitalized patients with COPD exacerbation a worse prognosis in BAP-65 and DeCOPD scores was related with higher average stay, more readmissions, lower Karnofsky Index and higher C reactive protein.