Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies.

Akaash K. Mishra,Jan Hellert,Natalia Freitas,Pablo Guardado-Calvo,Ahmed Haouz,J. Maximilian Fels,Daniel P. Maurer,Dafna M. Abelson,Zachary A. Bornholdt,Laura M. Walker,Kartik Chandran,François-Loïc Cosset,Jason S. McLellan,Félix A. Rey

Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies.

2021

Akaash K. Mishra
Jan Hellert
Natalia Freitas
Pablo Guardado-Calvo
Ahmed Haouz
J. Maximilian Fels
Daniel P. Maurer
Dafna M. Abelson
Zachary A. Bornholdt
Laura M. Walker
Kartik Chandran
François-Loïc Cosset
Jason S. McLellan
Félix A. Rey

Crimean-Congo hemorrhagic fever virus (CCHFV) is the most widespread tick-borne zoonotic virus, with a 30% case fatality rate in humans. Structural information on the CCHFV membrane fusion glycopro...

Keywords:

Virology
Neutralization
Crimean Congo hemorrhagic fever virus
Antibody
Biology

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