Expedient and Rapid Synthesis of 1,2,3-Triazolo[5,1-c]morpholines Through Palladium-Copper Catalysis.

A one-pot approach using palladium-copper as catalyst has been developed for the synthesis of morpholines fused with 1,2,3-triazole. Good regioselectivity, mild reaction conditions, high yields and short reaction time are the hallmarks of this method.