Prolonged anuria and aortic insufficiency in a child with Wegener's granulomatosis.
1982
A 16 year-old boy developed generalized Wegener's granulomatosis with rapidly progressive renal insufficiency resulting in prolonged anuria. He was treated with cyclophosphamide, prednisone and anticoagulants, and was maintained on peritoneal dialysis for seven weeks, after which he regained a GFR of 35 ml/min. Recovery of renal function following prolonged anuria has not been previously reported in a child with Wegener's granulomatosis. The patient also developed aortic regurgitation, a cardiac lesion not previously described in this disorder.
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