Influence of pyrazole, an inhibitor of alcohol dehydrogenase on the prenatal toxicity of ethanol in the rat.
1979
Pyrazole, a potent inhibitor of alcohol dehydrogenase, induced a high incidence of ocular and urinary bladder anomalies in the offspring of rats following treatment on gestational day 9. A single moderate dose of ethanol potentiated the teratogenic action of pyrazole, but alone did not affect embryonic development.
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