Increasing AR by HIF-2 α inhibitor (PT-2385) overcomes the side-effects of sorafenib by suppressing hepatocellular carcinoma invasion via alteration of pSTAT3, pAKT and pERK signals

Junjie Xu,Longbo Zheng,Jiang Chen,Yin Sun,Hui Lin,Renan Jin,Minyue Tang,Xiao Liang,Xiujun Cai

Increasing AR by HIF-2 α inhibitor (PT-2385) overcomes the side-effects of sorafenib by suppressing hepatocellular carcinoma invasion via alteration of pSTAT3, pAKT and pERK signals

2017

Junjie Xu
Longbo Zheng
Jiang Chen
Yin Sun
Hui Lin
Renan Jin
Minyue Tang
Xiao Liang
Xiujun Cai

Increasing AR by HIF-2 α inhibitor (PT-2385) overcomes the side-effects of sorafenib by suppressing hepatocellular carcinoma invasion via alteration of pSTAT3, pAKT and pERK signals

Keywords:

Molecular biology
Hepatocellular carcinoma
Sorafenib
Biology
In vivo
Hypoxia-inducible factors
Combination therapy
Hypoxia (medical)
Androgen receptor
Pharmacology
Medicine
In vitro

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