A Randomized Trial of Baby Triple P for Preterm Infants: Child Outcomes at 2 Years of Corrected Age

Objective To determine the efficacy of a hospital-based intervention that transitions into existing community support, in enhancing developmental outcomes at 2 years of corrected age in infants born at less than 32 weeks. Study design In total, 323 families of 384 infants born Results Mean gestational age of infants was 28.5 weeks (SD = 2.1), and mothers’ mean age was 30.6 years (SD = 5.8). A total of 162 families (n = 196 infants) were allocated to intervention and 161 families (n = 188 infants) received care-as-usual. There was no significant adjusted difference between treatment groups on dysregulation (0.2; 95% CI −2.5 to 3.0, P  = .9) externalizing (0.3; 95% CI −1.6 to 2.2, P  = .8), internalizing (−1.5; 95% CI −4.3 to 1.3, P  = .3), observed aversive (0.00; −0.04 to 0.04, P  = .9), or nonaversive behavior (−0.01; 95% CI −0.05 to 0.03, P  = .7). Intervention children scored significantly higher on cognition (3.5; 95% CI 0.2-6.8, P  = .04) and motor skill (5.5; 95% CI 2.5-8.4, P P  = .07). Conclusions Baby Triple P for Preterm Infants increases cognitive and motor skills but does not impact behavior. The results are evidence that hospital-based interventions can improve some developmental outcomes for infants Trial registration ACTRN 12612000194864.