Separation and recognition characteristics by MIP manufacture using supercritical CO2 technology

Abstract This research is focused on the experiment of molecular imprinting polymers by supercritical solvent technology as friendly-environmental process. Methyl methacrylate (MMA) monomer, methacrylic acid (MAA) monomer, VA (vanillic acid) with template and EGDMA (ethylene glycol dimethacrylate) with cross-linking agent were used for molecular imprinting polymers composition. The template has been eliminated by the Soxhlet extraction method, and the rate of elimination is ca. 95–98 %. The adsorption capacities of the synthesized molecular imprinting polymers were estimated using the kinetics and isotherms of restraint, Scatchard investigation, affinity distributions, the materials adsorption with template-like structure, α (selectivity parameter), and HPLC (high performance liquid chromatography) analysis. The evaluation result shows that the manufactured molecular imprinting polymers have highly selectivity and separation ability. It was also confirmed that there was a difference between the adsorption amounts with EGDMA contents. In this study, prepared molecular imprinting polymers had an advantage in adsorption selectivity where VA and its structural analog materials are present. These results show that the molecular imprinting polymers selectivity was increased using control the cross-linking agent.