Effect of dietary resveratrol supplementation on growth performance, immune response, serum biochemical indices, cecal microflora, and intestinal morphology of broiler chickens challenged with Escherichia coli

Abstract The present study was conducted to examine the effects of resveratrol (RSV) supplementation on growth performance, immune response, serum biochemical indices, cecal microflora, and intestinal morphology of broiler chickens challenged with E. coli. A total of 600 one-day-old broiler chickens were randomly allocated to 5 treatments with 6 replicates and 20 broiler chickens per replicate. The experimental treatments consisted of positive control (PC; without additive and not challenged), negative control (NC; without additive, but challenged with E. coli at d 7), and 3 additive treatments where broiler chickens were challenged with E. coli at d 7 and fed diets containing among 20 ppm colistin sulfate (CS), 300 ppm RSV (RSV300) or 600 ppm RSV (RSV600). Compared to NC treatment, dietary supplementation of CS, RSV300, and RSV600 increased body weight gain and decreased feed conversion ratio of broiler chickens challenged with E. coli (P