Aryl-Heteroaryl Derivatives as Novel Wake-Promoting Agents

Brigitte Lesur,Yin G. Lin,Val R. Marcy,Lisa D. Aimone,John A. Gruner,Edward R. Bacon,Sankar Chatterjee

Aryl-Heteroaryl Derivatives as Novel Wake-Promoting Agents

2013

Brigitte Lesur
Yin G. Lin
Val R. Marcy
Lisa D. Aimone
John A. Gruner
Edward R. Bacon
Sankar Chatterjee

In search of a next generation molecule to the novel wake-promoting agent modafinil, a series of aryl-heteroayl-derived wakefulness enhancing agents (in rats) was developed. From this work, compound 16 was separated into its enantiomers to profile them individually.

Keywords:

Organic chemistry
Chemistry
Aryl
Molecule
Stereochemistry
Modafinil
Enantiomer
Wake-Promoting Agents

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