Acute-on-chronic renal failure in the rat: functional compensation and hypoxia tolerance.

Background: We hypothesized that chronic renal parenchymal disease may predispose to acute renal failure (ARF), facilitating the induction of hypoxic medullary tubular injury.

Keywords:

• Renal function
• Hypoxia (medical)
• Acute tubular necrosis
• Endocrinology
• Nitric oxide
• Kidney disease
• Hypoxia-inducible factors
• Internal medicine
• Nephrology
• Diabetes mellitus
• Medicine
• Pimonidazole
• Medullary cavity
• Endothelin receptor

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