Patient-derived, three-dimensional spheroid cultures provide a versatile translational model for the study of organ-confined prostate cancer

Johannes Linxweiler,Markus Hammer,Stefanie Muhs,Moritz Kohn,Alexej Pryalukhin,Christian Veith,Rainer M. Bohle,Michael Stöckle,Kerstin Junker,Matthias Saar

Patient-derived, three-dimensional spheroid cultures provide a versatile translational model for the study of organ-confined prostate cancer

2019

Johannes Linxweiler
Markus Hammer
Stefanie Muhs
Moritz Kohn
Alexej Pryalukhin
Christian Veith
Rainer M. Bohle
Michael Stöckle
Kerstin Junker
Matthias Saar

Purpose To generate and characterize 3D spheroid suspension cultures from radical prostatectomy (RP) specimens as a versatile model system for organ-confined prostate cancer (PCa).

Keywords:

Prostatectomy
Prostate cancer
Pathology
Spheroid
Biology
Immunohistochemistry
Enzalutamide
Bicalutamide
Vimentin
Frozen section procedure
Docetaxel

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