Efficacy of demineralized bone matrix paste for maxillary sinus augmentation: A histologic and clinical study in humans

Objectives The aim of this study is to report the effect of paste type of demineralized bone matrix (DBM) on augmentation of maxillary sinus using clinical parameters. Study design Sinus augmentation with DBM was performed on 5 maxillary sinuses. This study included 5 patients, 4 men and 1 woman, aged from 41 to 67 years (mean age 55 years). After an average of 6 months' healing period, a core bone was obtained and stained for histologic analysis. Results All implants showed favorable osseointegration, and final restorations were completed without failure in all cases. Histologically, new bone formation was active around grafted bone and grafted bone was well integratied to the newly formed bone matrix. In histomorphometric analysis, vital bone volume was 25.2 ± 11.9%. Conclusion The DBM paste is clinically useful for the increase of bone volume in sinus augmentation, because of its favorable effect of new bone formation and easy handling.