Disseminated infection withSaccharomyces kluyveri in a patient with AIDS

A 47-year-old man with acquired immune deficiency syndrome was found to have disseminatedSaccharomyces kluyveri infection. The yeast was isolated from blood and cerebrospinal fluid. An autopsy revealed the presence of the microorganism in many organs including liver, kidneys, pancreas, spleen, lung, and brain. The case confirms a potential pathogenicity of yeasts of the genusSaccharomyces in patients with profound immune deficiency, especially in advanced HIV infection.