PD21-06 PENILE LOW INTENSITY SHOCK WAVE TREATMENT FOR PDE5I REFRACTORY ERECTILE DYSFUNCTION: A RANDOMIZED SHAM-CONTROLLED CLINICAL TRIAL

INTRODUCTION AND OBJECTIVES:Erectile dysfunction (ED) is a prevalent condition in males, affecting around 52% of men over 40 years. In recent years, the use of penile low intensity shockwave treatment (LI-ESWT) has been studied on vascular ED patients, because of its potential role in modifying several pathways of ED pathophysiology. The theoretical effect of LI-ESWT is based on its ability to increase the blood supply of treated areas. The objective of this trial is to investigate the effect of electromagnetic LI-ESWT on the erectile function of patients suffering phosphodiesterase type 5 inhibitor (PDE5i) refractory vascular ED.METHODS:Randomized, simple-blind, sham-controlled study. 76 patients with PDE5i-refractory ED completed the study. 40 men were treated with linear electromagnetic penile LI-ESWT (1 session/ week for 4 weeks, 5000 shocks/session, using 0.09 mJ/mm2 of energy density) and 36 were treated with a sham probe. Baseline and post-treatment (1, 3 and 6 months) evaluations were done using v...