Assembling polycyclic bisguanidine motifs resembling batzelladine alkaloids by double tethered Biginelli condensations.
2003
Double tethered Biginelli condensations furnish linked polycyclic bisguanidines or bisureas. Alteration of the bis-β-ketoester component allows bispolycyclic guanidine motifs to be constructed that resemble natural batzelladine alkaloids or have novel linkages.
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