Schwannomatose - primeiros casos relatados no Brasil

A dor neuropatica pode ser decorrente de diversas causas, entre elas a schwannomatose (SCH), uma doenca que acomete cerca de cinco mil brasileiros. A SCH e caracterizada por schwannomas multiplos e intensamente dolorosos. O diagnostico diferencial de SCH inclui especialmente as neurofibromatoses do tipo 1 e 2. Um caso tipico de SCH, provavelmente o primeiro registrado no Brasil, e apresentado e discutido em detalhes e dois outros casos subsequentes sao comparados quanto a determinados aspectos clinicos e radiologicos. Paciente feminina de 33 anos de idade foi admitida com queixas de dor e diminuicao progressivada forca no membro inferior esquerdo, havia cinco anos, associadas ao surgimento de nodulacoes muito dolorosas naquela regiao. Apresentava tambem duas manchas cafe com leite ( Neuropathic pain stems various sources including schwannomatosis (SCH), a disease that affects about five thousand Brazilians. SCH is characterized by multiple and intensely painful schwannomas. Differential diagnosis of SCH includes, especially, neurofibromatosis types 1 and 2. A typical case of SCH, possibly the first recorded in Brazil, is presented and discussed in detail and compared with two other subsequent cases with regards to selected clinical and radiological aspects. A 33 year-old female patient was admitted with pain and progressive loss of strength in the left lower limb for the past five years. These complaints were associated withthe appearance of very painful nodules in the same region. She also had two light brown (cafe-au-lait) spots (