Adenocarcinoma Represents the Most Frequent Pathological Type among Giant Ovarian Tumors Weighing More than 5,000 g

Objectives: The aim of this study was to evaluate the relation between pathology, operative complications and giant ovarian tumor weighing more than 5,000 g. Materials and Methods: We assessed eleven factors of 18 patients with giant ovarian tumors after surgery, including age, Performance Status (PS), total weight of the tumor, fluid weight of the tumor, pathology, side, preoperative serum D-dimer, rate of Deep Venous Thrombosis (DVT), intraoperative complications (rate of intra-abdominal adhesion and blood loss weight), and rate of postoperative ICU management. The subjects were divided into two groups: tumor weight ≥10,000 g (group ≥10,000 g) and tumor weight <10,000 g (group <10,000 g), and the same factors were compared between two groups. Results: The most frequent pathology of giant ovarian tumors weighing more than 5,000 g was found to be adenocarcinoma. Compared with eleven patients of group<10,000 g, seven patients out of group ≥10,000 g had significantly higher PS (median: 3 vs. 1, p<0.05), rate of intra-abdominal adhesion (85.7% vs. 9.0%, p<0.05), fluid weight (15.000 g vs. 4.400 g, p<0.05), blood loss weight (890 g vs. 130 g, p<0.05), and rate of postoperative ICU management (85.7% vs. 18.2%, p<0.05), respectively. Conclusions: Much attention should be paid to patients with giant ovarian tumors who confined to bed more than 50% of waking hours (PS 3 or 4), and aggressive surgery is recommended due to a frequent incidence of cancer.