OC.06.3 EFFICACY OF SEQUENTIAL THERAPY IN NEVER BEEN TREATED HELICOBACTER PYLORI PATIENTS WITH MULTI-RESISTANT STRAINS

(2183) subjects reported previous eradication therapy. BMI was ≤18 in 188 (4%), ≥18.1-≤25 in 2322 (50%), ≥25.1-≤30 in 1576 (35%) and ≥30.1 in the remaining 514 (11%) of the cases. H. pylori infection was detected in 1892 (40.7%) with a progressive increasing trend according to BMI (≤18: 36%; ≥18.1-≤25: 34%, ≥25.1-≤30: 46% and ≥30.1: 56%; p 50 years). Conclusions: H. pylori infection is significantly more frequent in obese than in normal weight individuals, irrespective of sex and age. Further studies, aiming to explore the role of hormones involved in the homeostasis food intake/satiety, such as ghrelin and obestatin, in linking H. pylori infection and obesity are needed.