The analysis of selected microelements in neonatal umbilical cord blood.

Microelements and trace elements play a vital role in the body. Low quantities of these elements are essential to ensure proper metabolic processes. The aim of the thesis was to determine levels of selected microelements (zinc, copper, iron, manganese, chromium and aluminium) in cord blood plasma, and to find out if the gestational age, gender and birth weight of a newborn affect these concentrations. The research was conducted on the cord blood of 71 newborns. Regarding the gestational age, three groups were distinguished: I – neonates born after 37 week of pregnancy (n=7), II – neonates born between 38 and 41 week (n=59), and III – neonates born after 42 week of pregnancy (n=5). Subsequently, another division concerned the gender: male (n=35) and female (n=36) neonates, as well as their weight: neonates with regular birth weight – 2.500-3.500 g (n=61), and neonates with high birth weight – over 3.500 g (n=10). The concentrations of zinc, copper, iron, manganese, chromium, and aluminium in cord blood plasma were determined on the basis of inductively coupled plasma atomic emission spectroscopy method. The results were subjected to statistical analysis using Statistica 10.0 software, with the assumption that the level of significance was p<0.05. The average concentrations of analysed elements in umbilical cord blood were the following: 18.67±3.05 μmol Zn dm–3, 16.60±2.64 μmol Cu dm–3, 23.32±3.29 μmol Fe dm–3, 0.96±0.21 μmol Mn dm–3, 2.81±0.14 μmol Cr dm–3 and 0.041±0.028 μmol Al dm–3, which is within the standard ranges, suggesting efficient regulating mechanisms of the developing foetuses. The research proved that the neonate’s gestational age, gender and birth weight