Hydrogels based on polymerized ionic Liquids as innovative Drug Carriers in controllable and individualized Dosage Forms
2020
Novel Polymerized Ionic Liquids (PILs)-based Hydrogels as Innovative Drug Delivery Systems are presented. The
embedding of drugs in hydrogels enables the “smart” delivery of bioactive molecules from drugs for an oral route of
administration. Therefore, a high mechanical strength as well as a favorable pH-dependent swelling behavior is required
which is shown in this study. A mechanical compression of PILs-based hydrogels up to 98.5% and a high swelling
behavior of poly(VEImBr) hydrogels in a solution with a high pH value is achieved. A significant lower swelling is
achieved in a solution with a lower pH value.
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