Lymphoma of Donor Origin Occurring in the Porta Hepatis of a Transplanted Liver

Non-Hodgkin's lymphoma after organ transplantation is a recognized complication of immunosuppressive therapy. A number of cases of post-transplantation lymphoma arising in allografted tissue have been described1. In addition, leukemia and lymphoma arising from donor cells after allogeneic bone marrow transplantation have been recognized2–8. Two cases of donor-related lymphoma in renal allografts have also been reported9,10. We describe the development of a lymphoma in a hepatic allograft recipient 4.5 months after orthotopic liver transplantation. Using a rapid technique based on the polymerase chain reaction (PCR), which makes use of a DNA sequence polymorphism at the D4S174 . . .