Compounds useful for treating retroviral infections pyranone.

The present invention relates to compounds of formula (I) and (II), which are pyran-2-ones, 5,6-dihydropyran-2-ones, 4-HIDROXIBENZOPIRAN-2-ones, 4-hydroxy-cycloalkyl [B ] pyran-2-ones, and derivatives thereof useful for inhibiting a retrovirus in a mammalian cell infected with said retrovirus, WHERE R {SUB 10} YR {SUB 20} taken together are formula (III) Y (IV).