Interferon-α Influences Tryptophan Metabolism without Inducing Psychiatric Side Effects

Marjolein Bannink,Durk Fekkes,Arthur R. Van Gool,Wim H. J. Kruit,Stefan Sleijfer,Bronno van der Holt,Alexander M.M. Eggermont,Gerrit Stoter,Michiel W. Hengeveld

Interferon-α Influences Tryptophan Metabolism without Inducing Psychiatric Side Effects

2007

Marjolein Bannink
Durk Fekkes
Arthur R. Van Gool
Wim H. J. Kruit
Stefan Sleijfer
Bronno van der Holt
Alexander M.M. Eggermont
Gerrit Stoter
Michiel W. Hengeveld

Background: Interferon-α (IFN-α) treatment is often associated with psychiatric side effects and has been found to lower the amount of tryptophan (TRP) available to the brain. The a

Keywords:

Tryptophan
Psychology
Internal medicine
Endocrinology
Psychiatry
Mood disorders
Side effect
Irritability
Tryptophan Metabolism
Interferon
interferon α

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