Tp-e interval and Tp-e/QT ratio before and after catheter ablation in patients with premature ventricular complexes

Aim: Tp-e/QT ratio is a novel marker of ventricular repolarization. The aim of the study is to evaluate the Tp-e interval and Tp-e/QT ratio before and after radiofrequency ablation (RFA) for patients with frequent premature ventricular complexes (PVCs). Patients & methods: The study included 151 consecutive patients who underwent RFA for treatment of symptomatic frequent PVCs. Results: Tp-e interval, Tp-e/QT ratio and Tp-e/QTc ratio (all p < 0.001) were significantly different before and after RFA. After the procedure, mean left ventricular ejection fraction of the population were significantly increased than before RFA (p < 0.001). There was a significant correlation between preprocedural Tp-e/QTc ratio and PVC burden in patients (p = 0.023). Conclusion: Our study shows that PVCs may have a negative effect on ventricular repolarization.