Gender disparity in the authorship of biomedical research publications during the COVID-19 pandemic.

BACKGROUND Gender imbalances in academia have been evident historically and persist today. For the past 60 years, we have witnessed the increase of participation of women in biomedical disciplines, showing that the gender gap is shrinking. However, preliminary evidence suggests that women, including female researchers, are disproportionately affected by the COVID-19 pandemic in terms of unequal distribution of childcare, elderly care and other kinds of domestic and emotional labor. Sudden lockdowns and abrupt shifts in daily routines have disproportionate consequences on their productivity, which is reflected by a sudden drop in research output in biomedical research, consequently affecting the number of female authors of scientific publications. OBJECTIVE The objective of this study is to test the hypothesis that the COVID-19 pandemic has a disproportionate adverse effect on the productivity of female researchers in biomedical field in terms of authorship of scientific publications. METHODS This is a retrospective observational bibliometric study. We investigate the proportion of male and female researchers who published scientific papers during the COVID-19 pandemic, using bibliometric data from biomedical preprint servers and selected Springer-Nature journals. We use the Ordinary Least Squares (OLS) regression model to estimate the expected proportions over time by correcting for temporal trends. We also use a set of statistical methods such as Kolmogorov-Smirnov (KS) test and Regression Discontinuity Design (RDD) to test the validity of results. RESULTS A total of 78,950 papers from bioRxiv, medRxiv and 62 selected Springer-Nature journals by 346,354 unique authors were analyzed. The acquired dataset consisted of papers that were published between January 1, 2019, and August 2, 2020. The proportion of women first authors publishing in biomedical fields during the pandemic drops on average 9.1% across disciplines (expected arithmetic mean y_est=0.39; observed arithmetic mean y=0.35; standard error of the estimate, S_est=0.007; standard error of the observation, σ_x =0.004). The impact is particularly pronounced for papers related to COVID-19 research, where the proportion of female scientists in the first author position drops by 28% (y_est=0.39; y=0.28;S_est=0.007;σ_x =0.007). When looking at the last authors, the proportion of women drops in average 7.9% (y_est=0.25; y=0.23;S_est=0.005;σ_x =0.003), while the proportion of women writing about COVID-19 as the last author decreased by 18.8% (y_est=0.25; y=0.21;S_est=0.005;σ_x =0.007). Further, by geocoding authors' affiliations, we show that the gender disparities become even more apparent when disaggregated by the country, up to 35% in some cases. CONCLUSIONS Our findings document a decrease in the number of publications by female authors in biomedical field during the global pandemic. This effect is particularly pronounced for papers related to COVID-19, indicating that women are producing fewer publications related to COVID-19 research. This sudden increase in the gender gap is persistent across the ten countries with the highest number of researchers. These results should be used to inform the scientific community of the worrying trend in COVID-19 research and the disproportionate effect that the pandemic has on female academics. CLINICALTRIAL