human gene predisposing to obesity and uses thereof.

A method for detecting the presence of, or predisposition to, obesity in a subject, the method comprising (i) providing a sample from the subject and (ii) detecting the presence of an alteration in the locus of the PPYR1 gene in said sample, said alteration being SNP 718 (nucleotide 803 C / T in SEQ ID No. 1).